Atendimento odontológico a pessoas com Síndrome de Down

Maria Eduarda Lima Correia dos Santos; Leila Cristina dos Santos Mourão

doi:10.61565/revista-aquila.i35.1065

Authors

Maria Eduarda Lima Correia dos Santos Universidade Veiga de Almeida
Leila Cristina dos Santos Mourão Universidade Veiga de Almeida

DOI:

https://doi.org/10.61565/revista-aquila.i35.1065

Keywords:

Down Syndrome, Dental care, Periodontal disease, Dental caries, Access to health services

Abstract

Down Syndrome (DS) is a genetic condition resulting from trisomy of chromosome 21, representing the most common chromosomal alteration in humans. Individuals with DS present specific phenotypic characteristics and associated systemic conditions that directly affect their overall and oral health. In dentistry, common findings include delayed tooth eruption, hypodontia, microdontia, increased susceptibility to periodontal disease, variable risk of dental caries, and a high prevalence of malocclusions. Furthermore, behavioral challenges and barriers to accessing oral healthcare services hinder adequate care for this population. This study aims to analyze, through a literature review, the main aspects related to dental care for people with Down Syndrome, addressing oral characteristics, preventive strategies, clinical management, and barriers to treatment access. Based on the analysis of the literature, the importance of a multidisciplinary, humanized, and individualized approach is emphasized to promote oral health and improve the quality of life of these patients.

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References

ABED, H.; TAJU, W. Perspectives on managing patients with Down’s syndrome among orthodontists in Saudi Arabia: A vignette and a COM-B analysis study. Journal of Orthodontic Science, [S. l.], v. 13, n. 1, p. 28, 2024. Available at: https://doi.org/10.4103/jos.jos_14_24. Accessed on: 28 Sep. 2026.

ALESSANDRI-BONETTI, A. et al. Prevalence of malocclusions in Down syndrome population. Medicina (Kaunas), v. 59, n. 9, p. 1657, 2023. Available at: https://doi.org/10.3390/medicina59091657. Accessed on: 28 Sep. 2026.

AMERICAN ACADEMY OF PEDIATRIC DENTISTRY. Management of dental patients with special health care needs. In: AMERICAN ACADEMY OF PEDIATRIC DENTISTRY. The Reference Manual of Pediatric Dentistry. Chicago: American Academy of Pediatric Dentistry, 2024. p. 332–340. Available at: https://www.aapd.org/research/oral-health-policies--recommendations/management-of-dental-patients-with-special-health-care-needs/. Accessed on: 28 Sep. 2026.

BOTERO, J. E.; RODRÍGUEZ-MEDINA, C.; AMAYA-SANCHEZ, S.; SALAZAR, C. L.; CONTRERAS, A. A comprehensive review of the relationship between oral health and Down syndrome. Current Oral Health Reports, v. 11, p. 15-22, 2024. Available at: https://doi.org/10.1007/s40496-024-00363-6. Accessed on: 28 Sep. 2026.

CASTILHO, A. R. F.; MARTA, S. N. Avaliação da incidência de cárie em pacientes com síndrome de Down após sua inserção em um programa preventivo. Ciência & Saúde Coletiva, v. 15, supl. 2, p. 1003-1008, 2010. Available at: https://doi.org/10.1590/S1413-81232010000800030. Accessed on: 28 Sep. 2026.

DEUS NETA, T. A. et al. Atendimento odontológico à criança com Síndrome de Down: revisão da literatura. Research, Society and Development, [S. l.], v. 10, n. 14, e552101422602, 2021. Available at: https://doi.org/10.33448/rsd-v10i14.22602. Accessed on: 28 Sep. 2026.

ELREFADI, R. et al. Oral health status in individuals with Down syndrome: a systematic review. Libyan Journal of Medicine, v. 17, n. 1, p. 2116794, 2022. Available at: https://doi.org/10.1080/19932820.2022.2116794. Accessed on: 28 Sep. 2026.

FERRARI, C.; MARINOPOULOU, E.; LYDON, H. Assessment of Chewing in Children With Down Syndrome. Behavior Modification, v. 47, n. 4, p. 845–869, 2023. Available at: https://doi.org/10.1177/01454455221129992. Accessed on: 28 Sep. 2026.

GAO, F.; WU, Y. Procedural sedation in pediatric dentistry: a narrative review. Frontiers in Medicine, v. 10, p. 1186823, 2023. Available at: https://doi.org/10.3389/fmed.2023.1186823. Accessed on: 28 Sep. 2026.

GHAFFARPOUR, M.; KARAMI-ZARANDI, M.; RAHDAR, H. A.; FEYISA, S. G.; TAKI, E. Periodontal disease in Down syndrome: predisposing factors and potential non-surgical therapeutic approaches. Journal of Clinical Laboratory Analysis, v. 38, n. 1–2, e25002, 2024. Available at: https://doi.org/10.1002/jcla.25002. Accessed on: 28 Sep. 2026.

HAMONARI, N. H. Salivary markers of oxidative stress and their relation to periodontal and dental status among children with Down syndrome. Cureus, v. 16, n. 11, e73852, 2024. Available at: https://doi.org/10.7759/cureus.73852. Accessed on: 28 Sep. 2026.

HASHIZUME, L. N.; MOREIRA, M. J. S.; HILGERT, J. B. Cárie dentária em crianças com síndrome de Down e fatores associados. RGO, Revista Gaúcha de Odontologia, Porto Alegre, v. 69, e20210044, 2021. Available at: https://doi.org/10.1590/1981-863720200004420200072. Accessed on: 28 Sep. 2026.

HUNG, M. et al. Navigating barriers to dental care for patients with Down syndrome: a scoping review of challenges and strategies. Children, [Basel], v. 12, n. 3, p. 330, 2025. Available at: https://doi.org/10.3390/children12030330. Accessed on: 28 Sep. 2026.

LIRA, A. D. L. S.; SILVA, C. I. R.; REBELO, S. T. C. P. Dentists’ actions about oral health of individuals with Down Syndrome. Brazilian Journal of Oral Sciences, Piracicaba, v. 14, n. 4, p. 256–261, out./dez. 2015. Available at: https://doi.org/10.1590/1677-3225v14n4a01. Accessed on: 28 Sep. 2026.

MARTINS, M. et al. The incidence of dental caries in children with Down syndrome: systematic review and meta-analysis. Dentistry Journal, v. 10, n. 11, 2022. Available at: https://doi.org/10.3390/dj10110205. Accessed on: 28 Sep. 2026.

MITSUHATA, C. et al. Characterization of the unique oral microbiome of children with Down syndrome. Scientific Reports, v. 12, p. 14545, 2022. Available at: https://doi.org/10.1038/s41598-022-18409-z. Accessed on: 28 Sep. 2026.

MÖHLHENRICH, S. C. et al. Orofacial findings and orthodontic treatment conditions in children and adolescents with Down syndrome. Journal of Orofacial Orthopedics, v. 84, p. 93–103, 2023. Available at: https://doi.org/10.1007/s00056-022-00375-0. Accessed on: 28 Sep. 2026.

MORAES, M. E. L. et al. Dental anomalies in patients with Down syndrome. Brazilian Dental Journal, [S. l.], v. 18, n. 4, p. 346–350, 2007. Available at: https://doi.org/10.1590/S0103-64402007000400014. Accessed on: 28 Sep. 2026.

MORISHIMA, S. et al. Salivary microbiome in children with Down syndrome: a case–control study. BMC Oral Health, v. 22, art. 438, 2022. Available at: https://doi.org/10.1186/s12903-022-02480-z. Accessed on: 28 Sep. 2026.

OLIVEIRA, A. C. et al. Uso de serviços odontológicos por pacientes com síndrome de Down. Revista de Saúde Pública, São Paulo, v. 42, n. 4, p. 693–699, 2008. Available at: https://doi.org/10.1590/S0034-89102008000400016. Accessed on: 28 Sep. 2026.

RICHTER, M. et al. Oral care experiences of children with Down syndrome: caregiver and dentist perspectives. Healthcare, v. 13, n. 9, 2025. Available at: https://doi.org/10.3390/healthcare13090999. Accessed on: 28 Sep. 2026.

RONDÓN-AVALO, S. et al. Association of Down syndrome with periodontal diseases: systematic review and meta-analysis. Special Care in Dentistry, v. 44, n.2, p. 360-368, 2024. Available at: https://doi.org/10.1111/scd.12892. Accessed on: 28 Sep. 2026.

SAITOS, P. et al. Parental perspectives on oral health and access to care in children with Down syndrome. Children, [Basel], v. 12, n. 5, p. 655, 2025. Available at: https://doi.org/10.3390/children12050655. Accessed on: 28 Sep. 2026.

SATO, T. et al. Landscape of driver mutations and their clinical effects on Down syndrome-related myeloid neoplasms. Blood, [S. l.], v. 143, n. 25, p. 2627–2643, 20 jun. 2024. Available at: https://doi.org/10.1182/blood.2023022247. Accessed on: 28 Sep. 2026.

SCALIONI, F. A. R.; CARRADA, C. F.; TAVARES, M. C.; ABREU, L. G.; RIBEIRO, R. A.; PAIVA, S. M. Oral health characteristics in children and adolescents with Down syndrome. Special Care in Dentistry, v. 44, n. 2, p. 542–549, 2024. Available at: https://doi.org/10.1111/scd.12883. Accessed on: 28 Sep. 2026.

VIEIRA, T. R.; PÉRET, A. de C. A.; PÉRET FILHO, L. A. Alterações periodontais associadas às doenças sistêmicas em crianças e adolescentes. Revista Paulista de Pediatria, São Paulo, v. 28, n. 2, p. 237–243, 2010. Available at: https://doi.org/10.1590/S0103-05822010000200017. Accessed on: 28 Sep. 2026.

WILLIS, J. R. et al. Oral microbiome in Down syndrome and its implications on oral health. Journal of Oral Microbiology, v. 13, n. 1, 2020. Available at: https://doi.org/10.1080/20002297.2020.1865690. Accessed on: 28 Sep. 2026.

YANG, R.; ZHAO, R.; CHAUDRY, F.; WANG, T.; BRUNTON, P.; KHURSHID, Z.; RATNAYAKE, J. Modern sedative agents and techniques used in dentistry for patients with special needs: a review. Journal of Taibah University Medical Sciences, v. 19, n. 1, p. 153–163, 2024. Available at: https://doi.org/10.1016/j.jtumed.2023.10.004. Accessed on: 28 Sep. 2026.

YEHIA, Z.; SILBEREISEN, A.; KOLETSI, D.; ARABZADEHTOUSI, M.; TSILINGARIDIS, G.; BOSTANCI, N. Efficacy of periodontal treatment modalities in Down syndrome patients: a systematic review and meta-analysis. Evidence-Based Dentistry, v. 25, n. 4, p. 213–214, 2024. Available at: https://doi.org/10.1038/s41432-024-01055-x. Accessed on: 28 Sep. 2026.